The Slaton sisters averaging over a thousand pounds, have always depended on each other for support. Now in their 30s, Amy wants to have children, but cannot due to her weight, while her elder sister Tammy is near bedridden.
While Amy reaps the benefits of weight-loss surgery, her sister Tammy worries that she gained weight during quarantine; a visit to urgent care gives Amy life-changing news; Tammy's family confronts her over her health
Tammy struggles to get back on the weight-loss wagon in order get approved for surgery, but this time, her brother, Chris, joins her on the journey. Amy must deal with one very big life-altering repercussion of having had her surgery
Tammy and Amy blame each other for their issues in therapy; when Tammy gets devastating news from Dr. Procter, her brother, Chris, makes a life-altering decision; a very pregnant Amy can't stop overeating, and the results are disastrous.
The Slatons are shocked by the cause of Amy's trip to the emergency room. Chris and Tammy see a new doctor, where Tammy must step on the scale again after a month of not sticking to her diet.
Tammy's new doctor gives her what feels like an insurmountable weight goal, but it's not the only challenge she's facing. Amy and Michael drop a bomb that changes everything.
Tammy's boyfriend, Jerry, comes to visit just in time to celebrate the sisters' favourite holiday: Halloween. Tammy's sister Misty questions Jerry's intentions. Amy has to face another weigh-in after her concerning appointment with Dr. Procter.
Amy counts down the days until her delivery with an eccentric photo shoot, while the family worries that Jerry is derailing Tammy's diet. Tammy reveals her big secret to Jerry.
When Tammy and Amy go see a psychic, they both get disturbing news. The family rallies together, and they are willing to try anything to help Tammy lose weight. Amy must face her worst fears when she's rushed to the ER.
Amy gets unsettling news about the birth of her baby as her high-risk pregnancy has last-minute complications; with their next weigh-in ahead of them, Chris and Tammy are cautiously optimistic until Tammy steps on the scale.
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