Major changes in the Russo household unsettle Blossom: Carol and Kennedy move in; Anthony and Shelly move out; and Joey hits the road with his baseball team.
Blossom and Nick fight over her resistance to change, particularly Carol, and she runs away from home to join Joey on his road trip.
Blossom is furious when Joey refuses to set her up on a date with his handsome but dumb teammate Richie, but has to admit he was right when a double date with Joey's dim new girlfriend Tanya bores her to distraction. Meanwhile, Kennedy finds a lost bulldog and is heartbroken when his owner claims him; and Shelly keeps picking on Anthony but won't say why - until we finally learn she is pregnant.
Blossom makes a video for the unborn baby of Anthony and Shelly to introduce him or her to the Russos' world; meanwhile, a veteran gives Joey the rookie treatment.
As Nick and Carol's wedding day arrives, there's something old (their exes at the bachelor party and bridal shower) and something blue (the bitter little flower girl, Kennedy).
Blossom struggles with a deceptively difficult school assignment in which she can express herself in any way she chooses, so Carol suggests that she simply write anything.
Blossom baby-sits Kennedy and her friend, a frightfully obnoxious little girl; meanwhile, Joey is like a babe in the woods when he's approached by a seasoned baseball groupie.
Six finds it hard to believe that she and Blossom weren't accepted at the same college. When Joey faces his first batting slump, Nick must revive his childhood persona of The Fishstick Man to help his son get his swing back. Anthony panics when it looks like Shelly is starting labor contractions.
Blossom dreams of herself as Blossom Gump, giving simple words of advice to Madonna and Michael Jackson, when in reality she'd rather be giving her opinions in the school newspaper.
When Shelly goes into labour, Blossom, Six and Joey are under the gun to get her to the hospital, while Anthony is being held at gunpoint in his ambulance.
Blossom sneaks off to a young-adult party, where she meets a guy who treats her like a mature young woman.
Blossom thinks the acting life might be for her, but her audition for a famous stage director doesn't play out as she hoped.
Blossom's wants some time alone with her new boyfriend to try to get something going, but there's too much going on in the house to get anything started.
Joey proves he's no dummy when he uses his scientific knowledge of anatomy to relieve Nick's stiff back.
Nick hopes sparks will fly when Blossom agrees to go out with the son of his old pal (who turns out to be happily gay); trapped by a flash flood, Joey and Six check into a hotel room together.
Vinnie announces he is transferring to UCLA because he misses Blossom; a new girlfriend spoils Joey.
Blossom is assaulted by her date, a popular football star, when she tries to fend off his aggressive advances.
Joey proposes to his old flame; Blossom gets a job at an ad agency run by Carol's old boyfriend, and Nick's bothered when Carol accepts an offer to be a consultant there.
Talia Shire asks Blossom to play the lead in a new movie she's directing - but the part requires Blossom to appear in the nude.
Blossom stubbornly refuses to accept a grade that she thinks is lower than she deserves - even if it means she won't graduate.
Joey proposes to Melanie; Nick decides to sell the house when Carol discovers she is pregnant; Blossom gets her first real job.
Blossom, Joey and Six discourage prospective buyers of the house, while Shelly and baby Nash plan to move back east.