Everyone else sees Wilfred as just a dog, but Ryan sees a crude and somewhat surly, yet irrepressibly brave and honest Australian bloke in a cheap dog suit. While leading him through a series of comedic and existential adventures, Wilfred the dog shows Ryan the man how to overcome his fears and joyfully embrace the unpredictability and insanity of the world around him.
Ryan forms a unique connection with his neighbor's dog after a failed suicide attempt.

Ryan tries to reconcile with his sister, and Wilfred is in for a shock at doggy day care as a result.

Wilfred reveals an extraordinary ability when Ryan takes him to a hospice to volunteer.

Wilfred persuades Ryan to help him get rid of Jenna’s boyfriend.

Ryan's resentment of his mother even grows when she moves in and becomes friends with Wilfred.

Just as Ryan finds happiness in his life, Wilfred begs him to sacrifice it for a larger purpose.
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